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大肠杆菌内毒素诱导兔体内、外血小板聚集,使血小板内cAMP水平降低。山莨菪碱能抑制内毒素诱导的血小板聚集,并提高血小板内cAMP的水平。山莨菪碱提高血小板内cAMP 的作用可为β-受体阻断剂心得舒阻断。
E. coli endotoxin induced rabbit platelet aggregation in vitro and in vivo, so that platelet cAMP levels decreased. Anisodamine inhibits endotoxin-induced platelet aggregation and increases platelet cAMP levels. Anisodamine enhance the role of cAMP in platelets for β-blockers heart Shu Shu.