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提出了一种用于低泄漏换料设计中可燃毒物优化配置的新方法，该方法直接采用组件内可燃毒物棒根数作为控制变量，以循环初组件平均功率峰因子最小为目标函数，用可变容差法求解可燃毒物配置的非线性规划问题。并将编制的优化程序ＮＬＰＯＴ对秦山核电站第二循环低泄漏换料进行了计算，取得很好效果。
A new method for optimal allocation of flammable toxins in low leakage refueling design was proposed. The method directly used the number of flammable toxins in the module as the control variable, and minimized the average peak power factor of the primary components in circulation as the objective function. A Nonlinear Programming Problem for Solving the Configuration of Combustible Poison with Variable Tolerance Method. And the optimized program NLPOT was calculated for the second cycle low leakage refueling of Qinshan Nuclear Power Station, and achieved good results.