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本文总结应用强地松治疗婴幼儿巨大血管瘤的疗效。方法是5～7.5mg/日,口服1～4周(常用量20～40mg/日3～4周),停药1～4周后重复用药。这样长期反复用药(2月～1.5年)治疗9例(女5例,男4例)。其中婴儿8例,6例可评定疗效,疗效均显著。长期坚持治疗4例,病变全消,在治疗过程和随诊中(3年3个月～4年),未见发育障碍或其它不良副作用。治疗前尽量排除结核、发热、胃肠道出血等症状。激素治疗作用机理尚不清楚。长期间断使用5～7.5mg/日强地松有效,但治疗时期过长是其缺点。强地松的远期副作用尚待确定。
This article summarizes the application of prednisone in the treatment of infantile giant hemangiomas. Method is 5 ~ 7.5mg / day, orally for 1 to 4 weeks (the amount of 20 ~ 40mg / day 3 to 4 weeks), discontinued 1 to 4 weeks after repeated medication. Such long-term repeated medication (February ~ 1.5 years) treatment of 9 cases (5 females, 4 males). Including 8 infants, 6 cases can be assessed efficacy, efficacy were significant. Long-term adherence to treatment in 4 cases, complete elimination of lesions in the course of treatment and follow-up (3 years 3 months to 4 years), no developmental disorders or other adverse side effects. Try to rule out tuberculosis before treatment, fever, gastrointestinal bleeding and other symptoms. The mechanism of hormone therapy is unclear. Long-term intermittent use of 5 ~ 7.5mg / day prednisone effective, but the treatment period is a disadvantage. Long-term side effects of pine need to be determined.