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目的 估算阳江高本底辐射慢性照射可能导致的实体癌超额相对危险。方法 基于自然村室内、外环境剂量和性别年龄别居留因子 ,估算研究群组每一个成员的累积剂量。假定剂量与癌症危险间存在线性关系 ,利用 1979～ 1995年的癌症死亡率资料 ,按照Poisson模型计算超额相对危险。结果 全部实体癌超额相对危险 (ERR)为 - 0 11(95 %CI,- 0 6 7,0 6 9) Sv。肝癌、鼻咽癌、肺癌和胃癌等前 4位癌症的ERR(95 %CI) Sv分别为 - 0 99(- 1 6 0 ,0 10 ) ,0 10 (- 1 2 1,3 2 8) ,-0 6 8(- 1 5 8,1 6 6 )和 - 0 2 7(- 1 37,2 6 9)。结论 未发现实体癌超额相对危险与剂量有关。
Objective To estimate the relative relative risk of solid cancers that may result from chronic radiation of high background radiation in Yangjiang. Methods The cumulative dose of each member of the study group was estimated based on the residential and outdoor environmental dose and age-specific residence factor in natural villages. Assuming a linear relationship between dose and risk of cancer, the excess relative risk was calculated using the Poisson’s model for cancer mortality data from 1979 to 1995. Results The overall relative risk of solid cancers (ERR) was -0.11 (95% CI, -0.67,06.9) Sv. The ERR (95% CI) Sv of the top 4 cancers including liver cancer, nasopharyngeal cancer, lung cancer and gastric cancer were -0.99 (-160, 0 10), 0 10 (-1 12 3 2 8), -0 6 8 (- 1 5 8, 1 6 6) and - 0 2 7 (- 1 37, 2 6 9). Conclusion No excess risk of solid cancer was found to be related to dose.