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Objective: To observe the therapeutic effect of integrated treatment of peripheral facial paralysis by stages in Qinghai plateau area. Methods: A total of 2 240 cases of peripheral facial paralysis treated with integrated approaches by stages were assigned to treatment group, and other 75 cases treated with acupuncture therapy assigned to control group. In treatment group, patients were treated with 1) medication (Prednisone, Dibazol, etc) and TDP ("special electromagnetic spectrum") plus ultrashort irradiation in the early stage; 2) TDP plus ultrasonic wave irradiation and acupuncture of Yangbai (阳白GB 14) to Yuyao (鱼腰EX-HN 4, penetration needling), etc in the medium stage; 3) medium-frequency irradiation and electroacupuncture (EA) of muscle motor joints and acupoints (GB-14, etc). Patients of control group were treated with conventional acupuncture therapy (GB-14, etc). Results: After treatment, of the 2 240 patients in treatment group, 2 072 (92.5%) were cured, 120 (5.3%) effective, 33 (1.5%) improved, and 15 (0.7%) failed. The total effective rate was 99.3%. Of the 75 cases in control group, 46 (61.3%) were cured, 16 (21.3%) effective, 9 (12.0%) improved, and 4 (5.4%) ineffective. The total effective rate was 94.6%. The cure rate and the total effective rate of treatment group were significantly higher than those of control group respectively (χ2=29.379, P