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[目的]对云南省化妆品质量及其安全性进行全面、系统地评价。[方法]对1996~2005年云南省常规监管的化妆品进行卫生化学、微生物学及毒理学项目检测分析,对化妆品引发的不良反应临床病例进行调查,开展祛斑、美白、祛痘3类功能化妆品的有毒有害成分的检测分析。[结果]进行卫生学检验的化妆品10年间合格率均较高,特殊用途化妆品的理化指标合格率较低。出现化妆品引起的激素依赖性皮炎、全身慢性汞中毒等新病种。对3类功能化妆品随机采样检测,合格率为:美白类52.4%,祛斑类39.5%,以汞超标为主;氢醌检出率为:美白类2.4%,祛斑类4.7%。[结论]建议尽快增加化妆品中其他禁限用物质的检测;应重视化妆品引起全身慢性汞中毒问题,加强祛斑、美白类化妆品的汞检测。
[Objective] To evaluate the quality and safety of cosmetics in Yunnan Province comprehensively and systematically. [Method] The routine chemical products, microbiology and toxicology items in Yunnan Province from 1996 to 2005 were tested and analyzed. The clinical cases of adverse reactions caused by cosmetics were investigated, and the cosmetics with freckle, whitening and acne treatment were developed Toxic and harmful components of the test analysis. [Result] The qualified rate of cosmetics for hygiene test was higher in 10 years, and the pass rate of physical and chemical indexes of special purpose cosmetics was lower. Cosmetic-induced hormone-dependent dermatitis, systemic chronic mercury poisoning and other new diseases. The three types of functional cosmetics random sampling test, pass rate: whitening class 52.4%, freckle class 39.5%, mainly mercury exceeded; hydroquinone detection rate: whitening class 2.4%, freckle class 4.7%. [Conclusion] It is suggested to increase the detection of other restricted substances in cosmetics as soon as possible. It should pay attention to the problem of chronic mercury poisoning caused by cosmetics and strengthen the mercury detection of freckle and whitening cosmetics.