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目的追踪观察1例重型β地贫并危重症甲型H1N1流感患儿,探讨其诊治经验。方法通过对1例重型β地贫并免疫性溶血性贫血脾切除术后合并危重症甲型H1N1流感患儿的症状体征、住院病情演变经过及相关实验室检查,以及行呼吸衰竭抢救治疗等观察并记录,对以上资料进行综合分析。结果入院后经免疫抑制治疗未能控制免疫性溶血性贫血,行脾切除术,术后合并甲型H1N1流感,并出现呼吸衰竭,经呼吸机辅助通气,积极抗感染,糖皮质激素等综合治疗后,患儿遗留肺纤维化,但输血间隔时间明显延长。结论儿童重型β地中海贫血并免疫性溶血性贫血行脾切除术后并危重症甲型H1N1流感起病急、进展快,及时综合治疗预后好。
Objective To observe and observe the diagnosis and treatment of one case of severe beta thalassemia and critically ill children with swine influenza A (H1N1). Methods One case of severe thalamic β-thalassemia and immune hemolytic anemia after splenectomy combined with severe symptoms and signs of H1N1 influenza in children with evolution of the hospital after the relevant laboratory tests and rescue treatment of respiratory failure and other observations And record, a comprehensive analysis of the above information. Results After admission, immunosuppressive therapy failed to control the immune hemolytic anemia, splenectomy, postoperative merger of influenza A (H1N1) and respiratory failure, ventilator assisted ventilation, active anti-infective, glucocorticoid and other comprehensive treatment After leaving children with pulmonary fibrosis, but blood transfusion interval was significantly longer. Conclusion Children with severe β-thalassemia and immune hemolytic anemia after the splenectomy and critically ill swine influenza A H1N1 influenza onset, rapid progress and timely comprehensive treatment of good prognosis.