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目的 :了解西咪替丁静脉滴注防治高原昏迷应激性上消化道出血的效果 ;方法 :将 71例高原昏迷患者随机分为两组 ,治疗组用西咪替丁 80 0mg/ 2 4h ,静脉滴注 ,根据并发上消化道出血情况测定胃液 pH值及胃液隐血试验 ;另一组为对照组 ;结果 :治疗组胃液pH值 4～ 6,上消化道出血率为 1 1 .3 2 % ;对照组胃液 pH值 2～ 3 ,上消化道出血率为44 .44 % ,P <0 .0 1 ;结论 :西咪替丁静脉滴注能有效降低高原昏迷应激性上消化道出血的发生 ,且应用愈早效果愈好。
Objective: To understand the effect of cimetidine intravenous drip on the prevention and treatment of plateau coma-induced upper gastrointestinal bleeding.Methods: 71 patients with altitude sickness were randomly divided into two groups, the treatment group with cimetidine 80 0mg / 2 4h, The other group as the control group; Results: The treatment group gastric juice pH value of 4 to 6, the upper gastrointestinal bleeding rate was 11.32% ; Control group gastric juice pH 2 ~ 3, upper gastrointestinal bleeding rate was 44.44%, P <0.01; Conclusion: cimetidine intravenous drip can effectively reduce plateau coma-induced upper gastrointestinal bleeding Occurs, and the sooner the better the effect.