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目的探讨内镜黏膜下套吸分离切除术治疗胃小间质瘤的可行性和安全性。方法经内镜下套吸分离切除21例患者胃小间质瘤,免疫组织化学检查标本CD117、CD34和Desmin的表达。术后第7天、第1、3及6个月和1年后分别复查胃镜检查,观察瘤体脱落和创面愈合情况。结果 21例病例中,20个瘤体完全分离,完全分离率为95.2%;1例患者瘤体未能完全分离,但随圈套器脱落而坏死。所有21例患者未出现穿孔、出血等并发症,未出现内镜下复发。结论治疗胃小间质瘤内镜下套吸分离切除术是安全、有效的操作技术,并具有操作简便,并发症少、切除彻底等优点,为胃小间质瘤的治疗提供新方法。
Objective To investigate the feasibility and safety of endoscopic submucosal drainage and resection for the treatment of gastric small interstitial tumors. Methods Twenty-one cases of gastric small interstitial tumor and immunohistochemical examination of CD117, CD34 and Desmin were excised by endoscopy. Gastroscopy was performed on day 7, 1, 3, and 6 months, and 1 year after operation, respectively. The tumor shedding and wound healing were observed. Results Of the 21 cases, 20 tumors were completely separated and the complete separation rate was 95.2%. One patient had failed to complete the tumor separation, but died of necrosis with the detached snare. All 21 patients did not appear complications such as perforation, bleeding and so on. No endoscopic recurrence occurred. Conclusion It is a safe and effective operation technique to treat endoscopic resection and resection of gastric small interstitial tumor. It has the advantages of simple operation, less complications and thorough resection, which provides a new method for the treatment of small glioblastoma.