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目的研究ST段抬高型急性心肌梗死患者梗死范围与B型尿钠肽(BNP)浓度的关系。方法测量63例ST段抬高型急性心肌梗死患者的BNP浓度观察其与心电图估测的心肌梗死范围的关系。结果大范围心梗组、中等范围心梗组、小范围心梗组3组的BNP浓度均显著高于对照组,3个心梗组之间进行两两比较,均有显著性差异。结论 BNP浓度与心肌梗死面积有相关性,梗死面积越大,BNP浓度越高。
Objective To investigate the relationship between the infarct size and the concentration of B-type natriuretic peptide (BNP) in patients with ST-elevation acute myocardial infarction. Methods The BNP levels of 63 patients with ST-segment elevation acute myocardial infarction were measured to determine their relationship with the range of myocardial infarction estimated by electrocardiogram. Results The BNP levels were significantly higher in the large-scale myocardial infarction group, the middle-sized myocardial infarction group and the small-scale myocardial infarction group than those in the control group. There were significant differences among the three groups. Conclusions There is a correlation between the concentration of BNP and the area of myocardial infarction. The larger the infarct size, the higher the concentration of BNP.