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毛霉菌是一种条件致病真菌,通常易感染于糖尿病和免疫抑制性病人。最常见的中枢神经系统受累是继发于鼻窦和眶部疾病向颅内的扩散。已有血源性孤立性脑毛霉菌病的个案性少见报道,这些病人可能与静脉内滥用海洛因有关。本文作者报道1例因用泼尼松和环磷酰胺引起免疫抑制而导致脑毛霉菌感染的病人。
Mucor is a conditionally pathogenic fungus that is usually predisposed to both diabetic and immunosuppressive patients. The most common central nervous system involvement is the secondary to the sinus and orbital disease spread to the brain. Individual cases of blood-borne solitary brain mucormycosis have been reported infrequently, and these patients may be associated with intravenous abuse of heroin. The authors report a case of a brain-mold infection caused by immunosuppression with prednisone and cyclophosphamide.