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目的：为研究子宫内膜异位症（ＥＭＴ）提供理想的动物模型。方法：取大鼠５５只，用手术移植法造模，并分别于术后４周、１２周，运用光镜、电镜和组化方法做进一步观察。结果：造模成功率在８５％（３７／４３）左右，移植物外观呈隆起的小包状，其体积在移植后４周及１２周时无明显变化（Ｐ＞０．０５）。异位内膜具有子宫内膜的基本组织结构，表面上皮糖原、ＲＮＡ含量明显低于正常内膜（Ｐ＜０．０１），非特异性烯醇化酶（ＮＳＥ）活性也呈下降趋势（Ｐ＞０．０５）。结论：该模型异位内膜生长稳定，具有类似于人类ＥＭＴ的形态学及组织化学特征
Objective: To provide an ideal animal model for the study of endometriosis (EMT). Methods: Fifty-five rats were enrolled in this study. Surgical transplantation was used to make the model. The rats were further observed by light microscopy, electron microscopy and histochemistry at 4 weeks and 12 weeks after operation. Results: The success rate of modeling was about 85% (37/43). The appearance of the implants showed a bulging pouch shape. The volume of the implants did not change significantly at 4 and 12 weeks after transplantation (P> 0.05). The ectopic endometrium had the basic structure of endometrium, the content of surface glycogen and RNA were significantly lower than that of normal endometrium (P <0.01), and the activity of non-specific enolase (NSE) was also decreased (P> 0.05). Conclusion: The model of ectopic endometrial growth was stable, with similar morphological and histochemical characteristics of human EMT