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为观察抗坏血酸（VitC）治疗肾综合征出血热（HFRS）的疗效,将640例HFRS患难随机分3组:A组（400例）予HFRS常规治疗;B组（130例）予VitC 3.0g加入10％葡萄糖25Oml,静滴,每天1次;C组（110例）予VitC 6.0g加入10％葡萄糖500ml,静滴,每天1次,B、C两组疗程均10天。结果示B、C组越期率高于A组,低血压休克、少尿、多尿天数及血小板、尿蛋白、肾功能复常时间均短于A组,治疗早期出血症状缓解率高于A组,疗效以C组为优,无明显副作用.说明VitC是治疗HRFS安全、有效的药物,剂量以6.0g/d为佳.
To observe the efficacy of ascorbic acid (VitC) in the treatment of hemorrhagic fever with renal syndrome (HFRS), 640 patients with HFRS were randomly divided into three groups: Group A (400 patients) received conventional HFRS; Group B (130 patients) 10% glucose 25Oml, intravenous infusion, once a day; C group (110 cases) to VitC 6.0g 10% glucose 500ml, intravenous infusion, once a day, B, C treatment groups were 10 days. The results showed that the overdue rates of group B and group C were higher than those of group A, and the duration of hypotension, oliguria, polyuria, platelets, urine protein and renal function recovery were shorter than that of group A. The remission rate of early bleeding was higher than A Group, the curative effect in group C is excellent, no obvious side effects.It is clear that VitC is a safe and effective drug for the treatment of HRFS, and the best dosage is 6.0g / d.