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We described a case of hemiconvulsion-hemiplegia-epilepsy syndrome treated by anatomical hemispherectomy. A 9-year-old boy who suffered from frequent convulsions at 1 month old, left hemiparesis, free of fever, followed by epileptic seizure at 4 years of age, and was diagnosed with hemiconvulsion-hemiplegia-epilepsy syndrome. Clinical manifestations and Wada test results confirmed that the impaired function of the affected cerebral hemisphere had been compensated by the normal hemisphere. The patient was treated by anatomic hemispherectomy. After the operation, the patient was seizure-free, but did not take any anti-epileptic drugs, and the hemiplegia was not aggravated. These findings demonstrated that the cortex controlling sensory and motor function has transferred.