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患者男,42岁,因浸润型肺结核用SM0.5每日二次;INH0.1每日三次治疗。20天后改每日SM0.75、INH0.3、TB_10.1,3天后全身瘙痒并出现密集皮疹,未就诊。6天后出现丘疹伴浆液渗出,奇痒、烦躁不安并有发热、腹疼等症状。血尿常规无异常。即停用一切抗痨药,给予激素、补液、抗过敏及对症治疗。一周后全身出现糜烂,四周后出现大量鳞屑手掌足底角化。六周后手足呈手套及袜套状剥脱。头发、眉毛、胡须及阴毛大量脱落。
Patient Male, 42 years old, infiltrated pulmonary tuberculosis with SM0.5 twice daily and INH0.1 three times daily. After 20 days to change daily SM0.75, INH0.3, TB_10.1, 3 days after systemic itching and dense rash, not treatment. After 6 days with papular effusion effusion, itching, irritability and fever, abdominal pain and other symptoms. No abnormalities in hematuria. That is, disable all anti-tuberculosis drugs, give hormones, rehydration, anti-allergy and symptomatic treatment. A week after the whole body erosion, a large number of scaly palms foot hyperkeratosis after four weeks. Hands and feet after six weeks was gloves and socks-like exfoliation. Hair, eyebrows, beard and pubic hair off.