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本文报告经病理组织学检查证实的星形细胞瘤790例,其中包括星形细胞瘤Ⅰ级181例,Ⅱ级282例及Ⅲ～Ⅳ级327例。本组患者男性明显多于女性,30～49岁年龄组好发。幕上与幕下星形细胞瘤的发生比例为5.4∶1。幕上者额叶最常累及,且星形细胞瘤Ⅲ～Ⅳ级多见,幕下则以小脑低恶度星形细胞瘤较多见。最常见的症状及体征为颅压增高、癫痫发作、偏瘫及小脑性共济失调。790例患者共行862次手术,其中69例(8.6%)。因肿瘤复发曾行二次以上手术。手术死亡率为7.7%。术后存活患者179例曾并用放疗和(或)化疗。根据我们对170例患者的随访观察,我们对可能与存活期长短有关的某些因素进行了讨论。
This article reports 790 cases of astrocytomas confirmed by histopathology, including 181 cases of grade I astrocytoma, 282 cases of grade II and 327 cases of grade III-IV. This group of patients significantly more men than women, 30 to 49 age group prone. The incidence of supratentorial astrocytomas was 5.4: 1. The frontal lobe most often involved, and more common astrocytoma Ⅲ ~ Ⅳ level, the lower beings cerebellar low-grade astrocytoma more common. The most common symptoms and signs of increased intracranial pressure, seizures, hemiparesis and cerebellar ataxia. A total of 862 operations were performed in 790 patients, 69 of them (8.6%). Due to tumor recurrence had more than two surgeries. Surgical mortality was 7.7%. One hundred and ninety-seven patients survived with radiotherapy and / or chemotherapy. Based on our follow-up of 170 patients, we discussed some factors that may be related to the length of survival.