论文部分内容阅读
实验先后两批,共取LACA小鼠390只。每批随机分为正对照、绿茶、复合及空白对照4组。正对照组和复合组每5天于小鼠尾静脉注射MNNG250μg一次,共7次,总量1.75mg;绿茶组和复合组每日用5％绿茶末普通饲料长期喂养,正对照组和空白对照组长期喂饲普通饲料。两批实验分别经96.4周及10 6周结束。结果绿茶不仅使肺发癌率从79.75％下降到13.59％,而且改变了肺肿瘤良、恶性及病理类型构成比,恶性肿瘤和癌前病变减少,对MNNG诱发小鼠肺癌及癌前病变可产生不同程度的预防作用。实验结果重复性好。
Two batches of experiments were conducted and 390 LACA mice were collected. Each batch was randomly divided into positive control, green tea, compound and blank control 4 groups. MNNG 250μg was injected into the tail vein of mice in the control and combination groups every 5 days for a total of 1.75mg; the green tea group and the combined group were fed with 5% green tea at the end of the day for a long period of time. The positive control group and the control group The group was fed normal feed for a long period of time. Two batches of experiments were completed at 96.4 weeks and 10 6 weeks respectively. Results The green tea not only reduced the lung cancer rate from 79.75% to 13.59%, but also changed the benign and malignant lung tumors and the ratio of pathological types. The malignant tumors and precancerous lesions were reduced. It produced MNNG-induced lung cancer and precancerous lesions in mice. Different degrees of prevention. The experimental results are reproducible.