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目的 :探讨HBV与日本血吸虫合并感染对幽门螺杆菌 (Hp)感染的影响。 方法 :利用Hp全菌抗原检测HBV、日本血吸虫单独或合并感染者血清抗HpIgG抗体。 结果 :HBV与血吸虫合并感染时 ,血清HpIgG抗体检出率 ( 85.7% )明显高于HBV或血吸虫单独感染 (阳性率分别为 4 5.5%和 72 .9% ) ,合并感染时血清抗体水平 ( 0 .87± 0 .1 0 )亦高于单独感染 ( 0 .77± 0 .2 0 ,0 .70± 0 .1 7) ,差异有显著性意义。HBV阳性者与HBV阴性者之间Hp 感染率和抗体水平相近。结论 :HBV和血吸虫合并感染对Hp感染具有协同作用
Objective: To investigate the influence of HBV and Schistosoma japonicum infection on Helicobacter pylori (Hp) infection. Methods: Serum anti-HpIgG antibodies of HBV and Schistosoma japonicum alone or in combination were detected by using Hp whole bacteria antigen. Results: The detection rate of HpIgG antibody was significantly higher in patients infected with HBV and schistosomiasis than in HBV or schistosomiasis alone (positive rates were 4. 5.5% and 72.9%, respectively). Serum antibody level (0 .87 ± 0. 1 0) was also higher than that of infection alone (0 .77 ± 0.20, 0.70 ± 0.17), the difference was statistically significant. Hp infection rate and antibody level are similar between HBV-positive and HBV-negative. Conclusion: The combined infection of HBV and schistosomiasis has a synergistic effect on Hp infection