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目的分析晚发支气管哮喘与慢性阻塞性肺疾病肺功能及气道反应性。方法选取本院2012年8月~2013年4月收治的54例晚发支气管哮喘患者与慢性阻塞性肺疾病患者,每组各27例,对两组患者的肺功能指标进行检测,主要包括1 s用力呼气容积(FEV1.0)、气道阻力(Raw)、最大呼气中断流量(MMEF)、最大呼气流量(PEF)以及残气容积/肺容量(RV/TLC)等。运用潮气量法对气道反应性进行测定,将醋甲胆碱作为激发试剂。结果慢性阻塞性肺疾病患者的MMEF、FEV1.0低于晚发支气管哮喘患者(P<0.05);晚发支气管哮喘患者的气道可逆性高于慢性阻塞性肺疾病患者(P<0.05)。结论对晚发支气管哮喘患者与慢性阻塞性肺疾病患者的肺功能进行检查,对气道反应性进行测定,能够提高诊断准确性和鉴别力,值得推广。
Objective To analyze the pulmonary function and airway responsiveness of late-onset bronchial asthma and chronic obstructive pulmonary disease. Methods Fifty-four patients with late-onset bronchial asthma and chronic obstructive pulmonary disease admitted from August 2012 to April 2013 in our hospital were selected, 27 patients in each group. The lung function indexes of two groups were detected, including 1 s forced expiratory volume (FEV1.0), airway resistance (Raw), maximum expiratory flow (MMEF), maximum expiratory flow (PEF) and residual volume / lung volume (RV / TLC) and so on. Tidal volume method was used to measure airway responsiveness and methacholine as an excitation reagent. Results The MMEF and FEV1.0 of patients with chronic obstructive pulmonary disease were lower than those of patients with late-onset bronchial asthma (P <0.05). The airway reversibility of patients with late-onset bronchial asthma was higher than that of patients with chronic obstructive pulmonary disease (P <0.05). Conclusions Lung function in patients with late-onset bronchial asthma and chronic obstructive pulmonary disease is examined, and airway responsiveness is measured to improve diagnostic accuracy and discriminating power and is worth promoting.