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目的:观察病理性近视黄斑劈裂（MF）玻璃体切割手术（PPV）联合内界膜剥除及空气填充治疗后黄斑区视功能变化。方法:单中心、回顾性病例研究。2018年10月至2019年10月于天津市眼科医院检查确诊的MF患者29例32只眼纳入研究。其中，男性3例4只眼，女性26例28只眼；年龄（63.00±3.45）岁。患眼等效球镜度数（-14.16±2.54）D；眼轴长度（29.14±1.04）mm。合并黄斑板层裂孔3例3只眼。患眼均行标准经睫状体平坦部三通道25G PPV联合内界膜剥除、空气填充治疗。手术前及手术后1、3、6个月采用黄斑完整性评估仪行黄斑区微视野检查，记录患眼黄斑10°范围内视网膜平均光敏感度（MS）、黄斑中心凹2°和4°固视率（P1、P2）、63%和95%双向正态分布椭圆面积（BCEA）。手术前与手术后不同时间MS、P1、P2、63%BCEA、95%BCEA比较行配对n t检验；固视稳定率比较行n χ2检验。n 结果:与手术前比较，手术后1、3、6个月，患眼MS提高差异均有统计学意义（n t=-2.208、-3.435、-4.919，n P=0.038、0.002、0.000）。手术后不同时间两两比较，仅手术后6个月与手术后1个月差异有统计学意义（n P=0.036）。与手术前P1、P2、63%BCEA、95%BCEA比较，患眼手术后P1、P2逐渐提高，63%BCEA、95%BCEA逐渐降低，但差异均无统计学意义（P1：n t=-1.595、-1.698、-1.966，n P=0.125、0.104、0.062；P2：n t=-1.622、-1.654、-1.707，n P=0.119、0.112、0.102；63%BCEA：n t=1.410、1.409、1.553，n P=0.172、0.173、0.135；95%BCEA：n t=1.412、1.408、1.564，n P=0.172、0.173、0.132）。手术后6个月，所有患眼黄斑区解剖复位，未发现全层黄斑裂孔、黄斑裂孔视网膜脱离等严重并发症。n 结论:PPV联合内界膜剥除及空气填充治疗MF安全、有效；手术后6个月内黄斑区MS内可显著提高。“,”Objective:To observe the changes of macular visual function after myopic foveoschisis (MF) and pars plana vitrectomy (PPV) combined with internal limiting membrane peeling and air filling.Methods:A single-center, retrospective study. From October 2018 to October 2019, 29 MF inpatients (32 eyes) in Tianjin Eye Hospital were included in this study. There were 3 males (4 eyes) and 26 females (28 eyes). The age was 63.00±3.45 years old. Equivalent spherical lens degree was -14.16±2.54 D, and axial length was 29.14±1.04 mm. Among them, 3 patients (3 eyes) had lamellar macular holes. All eyes underwent standard pars plana three-channel 25G PPV combined with internal limiting membrane peeling and air filling. Before surgery and at 1, 3, and 6 months after surgery, macular microperimetry was performed with a macular integrity assessment instrument, and the mean retinal sensitivitie (MS) within 10° of the macula, fovea 2° and 4° fixation rates (P1, P2), 63% and 95% bivariate contour ellipse area (BCEA) were recorded. The comparison of MS, P1, P2, 63%BCEA and 95%BCEA at different times before and after surgery was performed by paired n t test; the comparison of fixation stability rate was performed by n χn 2 test.n Results:Compared with before surgery, there were significant differences in the improvement of MS in affected eyes at 1, 3 and 6 months after surgery (n t=-2.208, -3.435,-4.919; n P=0.038, 0.002, 0.000). In the pairwise comparison at different times after surgery, only 6 months after surgery and 1 month after surgery were significantly different (n P=0.036). Compared with the preoperative P1, P2, 63%BCEA and 95%BCEA, the P1 and P2 of the eyes gradually increased after surgery, while the 63%BCEA and 95%BCEA gradually decreased, however, the difference was not statistically significant (P1: n t=-1.595,-1.698,-1.966; n P=0.125, 0.104, 0.062. P2: n t=-1.622,-1.654,-1.707; n P=0.119, 0.112, 0.102. 63%BCEA: n t=1.410, 1.409, 1.553; n P=0.172, 0.173, 0.135. 95%BCEA: n t=1.412, 1.408, 1.564; n P=0.172, 0.173, 0.132). Six months after surgery, all the eyes underwent anatomical repositioning of the macular area, and no serious complications such as full-thickness macular hole and macular hole retinal detachment were found.n Conclusions:PPV with internal limiting membrane peeling and air filling is an effective and safe method for MF, and the macular function improved significantly within 6 months postoperatively.