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目的:观察充气性视网膜固定手术治疗孔源性视网膜脱离（RRD）的疗效和安全性。方法:前瞻性病例系列研究。2020年1月至2021年12月于汕头国际眼科中心行充气性视网膜固定手术的RRD患者27例27只眼纳入研究。其中，男性10例，女性17例；年龄（36.0±11.8）岁。包括复发性视网膜脱离4只眼。所有患眼均行最佳矫正视力（BCVA）、光相干断层扫描检查。依据经单次玻璃体内注气后视网膜是否成功复位将患者分为单次手术组、二次手术组。患眼均行充气性视网膜固定手术，玻璃体腔注射0.3~0.5 ml Cn 3Fn 8，手术后次日行视网膜激光光凝封闭裂孔。手术后随访时间（15.0±6.0）个月。观察单次手术视网膜复位、BCVA恢复情况以及并发症发生情况。采用Mann-Whiteney检验或精确概率检验比较单次手术组、二次手术组患者的年龄、性别、视网膜脱离范围、视网膜裂孔数量以及手术前后的BCVA差异。n 结果:末次随访时，27只眼中，单次手术视网膜复位20只眼（74.1%，20/27）；二次手术视网膜复位7只眼（25.9%，7/27）。7只眼中，手术后裂孔未闭合、裂孔重新开放视网膜脱离复发、新发裂孔视网膜脱离复发分别为1、4、2只眼；再次行巩膜扣带手术或玻璃体切割手术后视网膜均复位。BCVA稳定、提高分别为14、13只眼。与单次手术组比较，二次手术组患眼视网膜脱离范围更广、手术前BCVA更差，差异均有统计学意义（n Z=-2.842、-2.233，n P<0.05）。出现一过性眼压升高5只眼；无感染性眼内炎、眼内出血、晶状体损伤等并发症发生。n 结论:充气性视网膜固定手术治疗RRD安全、有效。“,”Objective:To investigate the efficiency and safety of pneumatic retinopexy for rhegmatogenous retinal detachment (RRD).Methods:A prospective case series study. From January 2020 to December 2021, 27 eyes of 27 RRD patients in Joint Shantou International Eye Center were included. Among them, there were 10 males and 17 females; the mean age was 36.0±11.8 years old. There was recurrent retinal detachment in 4 eyes. Best corrected visual acuity (BCVA) and optical coherence tomography were performed. According to whether the retina was successfully reattached after a single intravitreal injection, the patients were divided into a single operation group and a second operation group. All eyes underwent pneumatic retinopexy, the patients received intravitreal injection of 0.3-0.5 ml 100% Cn 3Fn 8. On the next day, laser photocoagulation was performed around the retinal breaks. The mean follow-up time was 15.0±6.0 months. Outcome measures included single operation success rate, the BCVA at the last follow up and complications. The age, gender, extent of retinal detachment, number of retinal breaks, and preoperative and postoperative BCVA of patients in the single operation group and the second operation group were compared using Mann-Whiteney test or Fisher\'s exact test.n Results:Twenty of the 27 eyes (74.1%, 20/27) had retinal reattachment after single operation, 7 of the 27 eyes (25.9%, 7/27) had retinal reattachment after the second operation. Among the 7 eyes, retinal detachment recurrence after operation, retinal detachment recurrence after tear opening, and retinal detachment recurrence with new tears occurred in 1, 4, and 2 eyes, respectively; retinas were all reattached after scleral buckling or vitrectomy. The BCVA was stable and improved in 14 and 13 eyes, respectively. Compared with the single operation group, the retinal detachment in the second operation group was wider and the BCVA before operation was worse, the differences were statistically significant (n Z=-2.842,-2.233; n P<0.05). Transient intraocular pressure elevation occurred in 5 eyes; no complications such as infectious endophthalmitis, intraocular hemorrhage and lens damage occurred.n Conclusion:Pneumatic retinopexy is safe and effective in the treatment of RRD.