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目的探讨骨肉瘤远处软组织转移的诊治及预后。方法对自１９７６－１９９７年收治的５例骨肉瘤远处软组织转移患者的临床表现及诊治经过进行回顾性分析总结。结果软组织转移２例为首发转移，３例为肺转移出现后继发转移。单发３例，多发２例，部位包括：头皮、臀肌、胸肌、颈后肌肉。由于缺乏认识，均不同程度延误诊治。５例患者共行局部切除手术１０次，６次出现复发；３例接受放疗有部分疗效；２例接受化疗无效。随访２－１７个月（平均９．２个月），４例死于肺转移，１例死于脑转移。结论 对骨肉瘤患者的随访应警惕远处软组织转移的发生，早期诊断并积极治疗。手术切除应充分，可辅以放疗，改进全身治疗方案是提高生存率的关键。
Objective To investigate the diagnosis, treatment and prognosis of distant metastasis of osteosarcoma. Methods The clinical manifestations, diagnosis and treatment of distant metastases of 5 patients with osteosarcoma treated from 1976 to 1997 were reviewed retrospectively. Results Soft tissue metastasis was the first metastasis in 2 cases, and 3 cases were secondary metastasis after the occurrence of lung metastasis. Single 3 cases, multiple 2 cases, including: scalp, gluteal muscles, pectoral muscles, neck muscles. Due to a lack of awareness, the diagnosis and treatment were delayed to varying degrees. Five patients underwent local resection 10 times, 6 recurrences; 3 patients received partial radiotherapy; 2 patients received no chemotherapy. Followed up for 2-17 months (average 9.2 months), 4 died of lung metastasis, and 1 died of brain metastases. Conclusion Follow-up of osteosarcoma patients should be aware of the occurrence of distant soft tissue metastasis, early diagnosis and active treatment. Surgical resection should be sufficient, supplemented by radiotherapy, and improving systemic treatment is the key to improving survival.