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麝香保心丸由麝香、苏合香、蟾酥、牛黄、肉桂、冰片及人参等组成。临床用于心肌缺血引起的心绞痛、胸闷及心肌梗塞等症的治疗和预防[1]。为1995年版《中国药典》收载品种,其中有关麝香的定性定量方法均未收载。本文以麝香的主要有效成分之一麝香酮（Wuscone）[2]为指标,考察了麝香保心丸提取分离后,利用麝香酮苯腙衍生物分子量大,薄层层析时易与其它杂质相分离的原理,使供试液和麝香酮标准液分别与2,4-二硝基苯肼试液作用,生成桔黄色的麝香酮苯腙。然后分别点样于同一块薄层板上,以甲苯——乙酸乙酯（49:1）溶剂系统展开,用岛津CS-930型双波长薄层扫描仪测定样品中麝香酮的含量。
Shexiang Baoxin Pill consists of Musk, Suhexiang, Chinese wolfberry, bezoar, cinnamon, borneol and ginseng. Clinically used for the treatment and prevention of angina, chest tightness and myocardial infarction caused by myocardial ischemia [1]. For the 1995 version of the “Chinese Pharmacopoeia,” the collection of varieties, including qualitative and quantitative methods of musk are not included. In this paper, Musk ketone (Wuscone) [2], one of the main active components of musk, was used as an index to investigate the effect of the use of musk ketone phenylhydrazone derivatives on the molecular weight and thin layer chromatography. The separation principle allows the test solution and the muskone standard solution to react with the 2,4-dinitrophenylhydrazine test solution, respectively, to generate orange muskone benzoquinone. Then, they were spotted on the same thin layer plate and developed with toluene-ethyl acetate (49:1) solvent system. The content of muskone in the sample was measured with a Shimadzu CS-930 dual-wavelength thin layer scanner.