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对未被发现的心脏病病人的心房纤颤(房颤)曾认为是良性的,但最近Framingham研究组证明情况并非如此。虽然房颤的存在能使心脏功能减弱(正常情况下心房收缩时,排血量大约占心输出量的5～10％),而在无心脏病时,房颤的主要临床结局是引起血栓栓塞,尤其是脑血管意外。Framingham在30多年随访研究中,发现男性2,336人中有193人,女性2,873人中有183人发生房颤,32名男性(占房颤病人的16.6％)及11名女性(占6％)发生了单纯房颤。未发现亚临床甲状腺毒症,但可能是对有些病例的解释。通过病例对照设计,发现房颤可使脑血管意外发生率增加4倍,但与冠心病
Atrial fibrillation (atrial fibrillation) has been considered benign in undiscovered heart disease patients, but Framingham’s team recently showed otherwise. Although the presence of atrial fibrillation can diminish cardiac function (normal atrial contraction, the amount of blood transfusion accounted for about 5 to 10% of cardiac output), while in the absence of heart disease, the main clinical outcome of atrial fibrillation is thromboembolism , Especially cerebrovascular accident. In a 30-year follow-up study, Framingham found that 193 of 2,336 males, 183 of 2,873 females, 32 males (16.6% of AF) and 11 females (6%) developed AF A simple atrial fibrillation. No subclinical thyrotoxicosis was found, but it may be an explanation for some cases. Through case-control design and found that atrial fibrillation can increase the incidence of cerebrovascular accidents 4 times, but with coronary heart disease