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Chemotherapy-induced peripheral neuropathy(CIPN) is one of the most common and severe adverse effects related to cancer treatment.Unfortunately,although several agents and protocols have been proposed,no prophylactic strategies have yet to be proven useful.Therefore,new alternative therapies have been considered for CIPN prevention.Herbal medicine in Japan,called Kampo medicine,is derived from traditional Chinese medicine.Goshajinkigan(GJG) is a Kampo medicine,that is comprised of ten herbs.The aim of this work is to analyse the results of pre-clinical and clinical studies on the potential applications of GJG in CIPN prevention.
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common and severe adverse effects related to cancer treatment. Unfortunately, although several agents and protocols have been proposed, no prophylactic strategies have yet to be proven useful.Therefore, new alternative therapies have was considered for CIPN prevention. Herbal medicine in Japan, called Kampo medicine, is derived from traditional Chinese medicine. Goshajinkigan (GJG) is a Kampo medicine, that is comprised of ten herbs. AIM This work is to analyze the results of pre -clinical and clinical studies on the potential applications of GJG in CIPN prevention.