论文部分内容阅读
作者曾对除外染色体疾病、软骨发育不良、甲状腺机能减退的25名4—16岁的矮小儿童进行了研究。这些病人在试验前整夜禁食并卧床休息。对每一个儿童行肘前静脉插管取血,在注射药物前15分钟至注射后2小时之间,每隔15分钟取血一次。试验开始按2μg/kg的剂量给以生长激素释放激素(GHRH-44)或0.1—0.5U/Kg的常规胰岛素。分别在15、30、45、60和120分钟后测定血浆GH含量。血中葡萄糖值下降50%或更多。GH对GHRH的反
The authors studied 25 young children aged 4-16 years with exclusion of chromosomal disorders, achondroplasia, and hypothyroidism. These patients fasted and slept in bed overnight before the test. Blood was drawn into the anterior venous catheter for each child, and blood was taken every 15 minutes between 15 minutes before the injection of the drug and 2 hours after the injection. The trial started with growth hormone releasing hormone (GHRH-44) or 0.1-0.5 U / Kg of conventional insulin at a dose of 2 μg / kg. Plasma GH levels were measured at 15, 30, 45, 60 and 120 minutes respectively. Blood glucose value decreased by 50% or more. GH against GHRH