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目的:观察胶质母细胞瘤扩大全切除的疗效。方法:对75例胶质母细胞瘤患者采用术中MRI监测下进行扩大全切除、全切除和部分切除手术,观察患者中位生存期和2年生存率。结果:扩大全切除患者中20/31例(64.52%)生存期超过2年,中位生存期为24.71个月;全切除患者中6/18例(33.33%)生存期超过2年,中位生存期为17.28个月;而部分切除患者中无一例生存期超过2年,中位生存期为11.15个月。结论:胶质母细胞瘤扩大全切除较全切除和部分切除可明显延长患者的术后生存期,术中MRI监测是保证全切除和扩大全切除的重要方法。
Objective: To observe the effect of enlarging the total resection of glioblastoma. Methods: Totally 75 patients with glioblastoma underwent total resection, total resection and partial resection with intraoperative MRI. The median survival time and 2-year survival rate were observed. Results: 20/31 (64.52%) patients with extended total resection had a median survival of 24.71 months over 6 years, and 6/18 patients (33.33%) underwent total survival of more than 2 years Survival was 17.28 months; while none of the partially resected patients had a survival of more than 2 years, with a median survival of 11.15 months. CONCLUSION: Gallbladder tumor enlargement and total resection can significantly prolong the postoperative survival time of patients. MRI monitoring during operation is an important method to ensure total resection and complete resection.