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用放射免疫分析法（ＲＩＡ）测定了８０例糖尿病患者血、尿β２－ＭＧ及原Ａｌｂ的含量。结果发现糖尿病患者血、尿β２－ＭＧ与尿Ａｌｂ的含量显著高于对照组；Ⅰ型糖尿病组显著高于Ⅱ型糖尿病组；均有显著性差异（Ｐ＜０．００１）．结果说明糖尿病患者易并发肾脏病变。因此，β２－ＭＧ、ＡｌｂＲＩＡ对预报和观察糖尿病肾病的发生、发展有极重要的意义．
Radioimmunoassay (RIA) was used to determine the content of blood and urine β2-MG and Alb in 80 diabetic patients. The results showed that blood, urine β2-MG and urinary Alb in diabetic patients were significantly higher than those in control group. The level of type 1 diabetes mellitus was significantly higher than that of type 2 diabetes mellitus (P <0.001). The results suggest that patients with diabetic nephropathy easily complicated. Therefore, β2-MG, AlbRIA is very important for the prediction and observation of the occurrence and development of diabetic nephropathy.