Using the improved position specific scoring matrix and ensemble learning method to predict drug-bin

• 作 者: Juan Li Yongqing Zhang Wenli Q
• 机 构: CollegeofChemistry,CollegeofComputerScience
• 出 处: 自然科学期刊(英文)
• 发表日期: 2012年5期
• 关键词: Drug-Binding SITE Prediction POSITION Specific SCORING Matrix ENSEMBLE Learning

Identification of the drug-binding residues on the surface of proteins is a vital step in drug discovery and it is important for understanding protein function. Most previous researches are based on the structural information of proteins, but the structur