论文部分内容阅读
对早妊流产病人放置昆布前后之血浆前列腺素代谢产物,13、14—去氢—15—酮前列腺素2α(PGFM) 作了测定。 71例妇女随机分为试验组或对照组。宫颈扩张度在放置昆布前为3.0±0.1mm,放置15小时后达10.2±0.2mm (P<0.001)。血浆PGFM在放置前为28.3±2.4微微克/毫升,昆布取出时为43.0±2.7微微克/毫升 (P<0.001),对照组之PGFM浓度无变化。血浆PGFM浓度与病人症状无关。昆布的作用主要为其本身之吸水性,膨胀后造成宫颈机械性扩张,也可能改变子宫前列腺素F_2α的释放或降解,故生化及机械作用可能为昆布促进宫颈扩张之作用机制。
The plasma prostaglandin metabolites, 13,14-dehydro-15-ketoprostaglandin-2alpha (PGFM), were measured before and after the kelp was placed in patients with early pregnancy induced abortion. 71 women were randomly divided into experimental group or control group. Cervical dilatation was 3.0 ± 0.1 mm before placing kelp and 10.2 ± 0.2 mm after 15 hours (P <0.001). Plasma PGFM was 28.3 ± 2.4 pg / ml prior to placement and 43.0 ± 2.7 pg / ml (P <0.001) at the time of kelp removal, with no change in PGFM concentration in the control group. Plasma PGFM concentration has nothing to do with the patient’s symptoms. The main function of the kelp is its own water absorption, resulting in mechanical expansion of the cervix after expansion, may also change the release or degradation of uterine prostaglandin F_2α, so the biochemical and mechanical effects may be the mechanism of kelp to promote cervical dilatation.