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反复治疗仍然痰菌阳性或结核病活动的病例,有人称之为“难治性肺结核”。这类患者治疗困难,传染性持续,长期影响健康,成为近年来临床的难点和热点,有关“难治性肺结核”的概念、成因和对策方面的探讨颇多,认识上各有侧重。湖北省武汉市作为《第五轮中国全球基金耐多药结核病防治项目》试点地区之一,复述有关文献,区分所谓难治、治疗障碍与耐多药概念,如何在初治、复治患者中发现耐多药病例,对于执行全球基金结核病项目是有帮助的。
Repeated treatment of sputum is still positive or tuberculosis activity cases, some people call it “refractory tuberculosis.” The treatment of these patients is difficult, contagious, long-term impact on health has become a clinical hot point in recent years and hot spots on the concept of “refractory tuberculosis”, causes and measures to explore a lot of understanding of each have their own focus. Wuhan City, Hubei Province as one of the pilot areas of the “Fifth Round of Global Fund to Fight MDR-TB Prevention and Cure in China Fund”, reviewing the relevant literature to distinguish the so-called refractory, treatment-resistant and multidrug-resistant concepts. Discovering multidrug-resistant cases can be helpful in implementing the Global Fund’s tuberculosis project.