Electrical stimulation of the sacral nerve anterior root following induced bladder detrusor contract

来源 :中国神经再生研究(英文版) | 被引量 : 0次 | 上传用户:xiaoshuishe
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The sacral nerve anterior root consists of parasympathetic nerves(dominating urinary bladder detrusor)and somatic motor nerves(dominating urethral sphincter),and electrical stimulation to the sacral nerve anterior root induces simultaneous contraction of the bladder detrusor and urethral sphincter.Accordingly,urethral pressure exceeds intravesical pressure,resulting in little or no urination,kidney damage,and trembling of lower limbs due to high intravesical pressure.In the present study,sacral nerve posterior roots were transected in a spastic bladder rabbit model,followed by three-pole electrode and long-pulse electrical stimulation to the sacral anterior root.Intravesical and urethral pressures were simultaneously measured to verify the feasibility of anode inhibition to the sacral anterior root following induced detrusor contraction.As stimulus intensity increased,somatic motor nerves were increasingly inhibited; with a stimulus pulse width of 300 μs and stimulus current of 1.05 mA,urethral pressure was zero and average intravesical pressure was 3.84 kPa.In addition,detrusor contraction was displayed,and lower extremity trembling was significantly reduced.Three-pole electrode and long-pulse electrical stimulation to the sacral nerve anterior root induced detrusor contraction and inhibited low extremity trembling under electrical stimulation.
其他文献
目的 观察胺碘酮联合美托洛尔治疗慢性心力衰竭并室性心律失常疗效和安全性.方法 68例慢性心力衰竭并室性心律失常患者,按照用药方案的不同分为对照组和实验组,每组34例.对照
期刊
目的 探讨苦参碱注射液联合阿德福韦酯对拉米夫定耐药慢性乙型肝炎患者病毒学及肝纤维化指标的影响.方法 94例拉米夫定耐药的慢性乙型肝炎患者,按随机数字表法分为对照组和观
Epileptic seizures induce overexpression of P-glycoprotein in the blood-brain barrier. However, it is unclear whether hippocampal neurons also overexpress P-gly
目的 探讨胃癌晚期采用多西他赛+雷替曲塞治疗的临床效果及对分泌型糖蛋白Dickkopf-1(DKK-1)水平和三叶因子家族蛋白3(TFF3)水平的影响.方法 48例胃癌晚期患者,遵照双盲法分
Epilepsy can lead to the changes in neurons residing in the dentate gyrus. The present study aimed to observe the cell dividing features following epilepsy in a
目的 研究分析低分子肝素在急性肾功能衰竭血液透析(HD)治疗中的抗凝作用.方法 100例急性肾功能衰竭患者,按治疗时间先后顺序分为研究组与参照组,每组50例.接受血液透析过程
Intraperitoneal injection of recombinant human interleukin-2(rhIL-2)inhibits neuronal apoptosis in the chronic ocular hypertension retinal ganglion cell layer.I
Artificial facial nerve prostheses are thought to restore eye-closed function in peripheral facial paralysis patients.At present,however,there is no adequate qu