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为了解西酞普兰在我国应用的临床疗效和不良反应，２５例抑郁症病人接受了该药治疗，剂量为２０～６０ｍｇ／ｄ，疗程６周。使用Ｈａｍｉｌｔｏｎ抑郁量表（ＨＲＳＤ）和临床总体印象量表（ＣＧＩＳ）评定疗效，同时记录药物的副作用。结果：上述２种量表在治疗前后的得分均有显著下降，显效率为８１％，且副作用轻微。因子分析发现，该药对抑郁焦虑因子的作用快而强，但睡眠因子在治疗前后无显著变化。结果表明，西酞普兰为一种安全、有效、服用方便的抗抑郁药物。
In order to understand the clinical efficacy and side effects of citalopram in our country, 25 patients with depression received the drug at a dosage of 20-60 mg / d for 6 weeks. The Hamilton Depression Rating Scale (HRSD) and the Clinical Total Impression Scale (CGIS) were used to assess the efficacy and the drug side effects were recorded. Results: The scores of the two kinds of scales before and after treatment all decreased significantly, the effective rate was 81%, and the side effects were mild. Factor analysis found that the drug on the role of depression and anxiety factor faster but stronger, but no significant changes in sleep factor before and after treatment. The results show that citalopram as a safe, effective, easy to take antidepressants.