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目的：探讨卡培他滨维持治疗晚期结直肠癌的临床效果与价值。方法：以我院于2015年3月—2016年3月间收治的62例晚期结直肠癌患者作为研究对象，随机分为对照组和观察组各31例。给予对照组5-氟尿嘧啶治疗，给予对照组卡培他滨治疗，对比两种治疗模式的临床效果差异。结果：观察组的治疗总有效率及不良反应发生率均明显优于对照组，两组差异有统计学意义（P＜0.05）。结论：对晚期肠癌患者实施卡培他滨治疗，效果显著，安全性高，值得推广和应用。“,”Objective: To explore the clinical effect and value of maintenance therapy for advanced colorectal cancer. Methods:62 cases of advanced colorectal cancer were randomly divided into the control group and the observation group, 31 cases in our hospital between March 2016 and March 2015. 5- treatment was given to the control group, and the control group was treated with the treatment of the patients with the control group. The clinical effects of the two treatments were compared.Results:the total effective rate and adverse reaction rate in the observation group were significantly better than those in the control group, the difference was statistically significant (P < 0.05) (two). Conclusion: the treatment of patients with advanced carcinoma of the colon, the effect is obvious, the safety is high, it is worth to popularize and apply.