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本文报道用碳酸锂纠正何杰金氏病患者由放疗所致的中性白细胞减少。 69例何杰金氏病患者参与了试验。33例中性白细胞减少患者在整个放疗期间每日口服碳酸锂900mg,持续1～7周;对照组为25例。对照组与治疗组的对比主要根据预后的症状和治疗的规模。其余11例在相同的治疗方案下,于联合治疗中断之间给予碳酸锂。在放疗的每一个阶段,以及应用碳酸锂前、后对所有病人的外周血液的中性白细胞绝对含量进行评价。结果:在放疗各阶段,治疗组19例患者外周血液的平均中性白细胞含量为53.6％。
This article reports the use of lithium carbonate to correct Hodgkin’s disease caused by radiotherapy neutropenia. 69 cases of Hodgkin’s disease patients participated in the trial. 33 patients with neutropenia oral lithium carbonate 900mg daily for 1 to 7 weeks; control group of 25 patients. Comparison of the control group and the treatment group mainly based on the prognosis of the symptoms and the size of the treatment. The remaining 11 patients were given lithium carbonate between the treatment interruptions under the same treatment regimen. Peripheral blood neutrophils were evaluated for absolute neutrophil content at each stage of radiotherapy and before and after application of lithium carbonate. Results: In each stage of radiotherapy, the mean neutrophilic leukocyte content in peripheral blood of the 19 patients in the treatment group was 53.6%.