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患者女,46岁。主诉:上唇丘疹2个月。现病史:患者2个月前无明显诱因上唇右侧出现一红色丘疹,偶有痒感,未予诊治。丘疹逐渐增大,搔抓后有少量渗血,于2013年12月10日来我院就诊。患者既往体健,否认患有其他疾病,家族中无类似疾病患者。体格检查:系统检查无异常,浅表淋巴结未触及增大。皮肤科检查:上唇右侧见一约黄豆大淡红色丘疹,质中,境界清楚,丘疹表面尚光滑,可见表皮剥脱伴少许鳞屑(图1)。实验室检查:血、尿常规正常,肝、肾功能,电解质及血糖血脂正常。心电图、胸部X线片无异常。皮损组织病理检查:肿瘤组织向内、外生长,向内增生部分呈柱状,中心可见隐窝形成,内有角质栓(图2A),
Female patient, 46 years old. Chief complaint: upper lip papules 2 months. Current medical history: patients 2 months ago no obvious incentive on the right lip appear a red papules, occasional itching, no diagnosis and treatment. Papules gradually increased, a small amount of bleeding after scratching, in December 10, 2013 to our hospital. Past physical health of patients, denied suffering from other diseases, no similar family disease patients. Physical examination: no abnormalities in the system examination, no increase in superficial lymph nodes. Dermatology examination: See the right side of the upper lip about a large pink papules, quality, the realm of clear, papular surface is still smooth, visible skin stripping with a little scale (Figure 1). Laboratory tests: blood, urine normal, liver, kidney function, electrolytes and blood glucose, blood lipids normal. ECG, chest X-ray no abnormalities. Skin lesions histopathological examination: tumor tissue inward and outward growth, inward part of the columnar columnar, the center visible crypt formation, there are keratin (Figure 2A),