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目的:观察总结尼莫地平在治疗急性外伤引起脑肿胀的临床疗效。方法:对2007年4月—2009年4月治疗的44例经头颅CT证实的外伤性脑肿胀病人,随机分为尼莫地平治疗组和对照组进行观察,治疗前后比较两组病人的蛛网膜下腔出血、脑肿胀程度,脑挫裂伤水肿体积及神经功能缺损评分差。结果:尼莫地平组较对照组蛛网膜下腔出血吸收、脑肿胀程度,脑挫裂伤水肿体积及神经功能缺损评分差疗效均非常明显(P<0.05),且应用尼莫地平愈早,效果愈明显。结论:尼莫地平早期治疗急性外伤引起脑肿胀可明显改善病情及预后。
Objective: To observe and summarize the clinical efficacy of nimodipine in the treatment of acute traumatic brain swelling. Methods: Forty-four patients with traumatic brain swelling confirmed by skull CT scan from April 2007 to April 2009 were randomly divided into nimodipine treatment group and control group. Before and after treatment, the arachnoid Inferior vena cava hemorrhage, degree of brain swelling, edema volume of cerebral contusion, and poor neurological deficit score. Results: Compared with the control group, the nimodipine group had better effect of absorption of subarachnoid hemorrhage, degree of brain swelling, edema volume of cerebral contusion and neurological deficit score (P <0.05) The effect is more obvious. Conclusion: Early nimodipine treatment of acute traumatic brain swelling can significantly improve the condition and prognosis.