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目的探讨中西医结合治疗消化性溃疡的临床价值。方法89例消化性溃疡患者,随机分为治疗组及对照组。治疗组45例,给予柴胡桂枝汤加减,配合奥美拉唑(20mg,2次/d)、阿莫西林(750mg,2次/d),疗程4周;对照组44例,给予奥美拉唑(20mg,2次/d)和阿莫西林(750mg,2次/d),疗程4周。观察两组症状的缓解率及不良反应,并于疗程结束后复查胃镜,观察Hp根除率、溃疡有效率。结果治疗组Hp根除率为89.7%(35/39),对照组为68.6%(24/35)(χ2=5.116,P<0.05);治疗组和对照组症状缓解率和不良反应发生率分别为93.3%,11.1%和88.6%,20.5%,两组间无统计学差异(P>0.05);治疗组溃疡有效率为91.1%、对照组为72.7%,两组比较有显著性差异(χ2=5.099,P<0.05)。结论中西医结合治疗消化性溃疡其疗效优于单纯西医治疗,值得临床进一步推广。
Objective To explore the clinical value of integrated traditional Chinese and western medicine in the treatment of peptic ulcer. Methods 89 patients with peptic ulcer were randomly divided into treatment group and control group. In the treatment group, 45 cases were treated with Chaihu Guizhi Decoction, with omeprazole (20mg twice a day) and amoxicillin (750mg twice a day) for 4 weeks. In the control group, 44 cases were given omeprazole (20mg, 2 times / d) and amoxicillin (750mg, 2 times / d) for 4 weeks. The relief rate and adverse reactions of the two groups were observed. Gastroscopy was performed after the end of treatment to observe the eradication rate of Hp and the effective rate of ulcer. Results Hp eradication rate was 89.7% (35/39) in the treatment group and 68.6% (24/35) in the control group (χ2 = 5.116, P <0.05). The rates of symptom relief and adverse reactions in the treatment group and the control group were 93.3%, 11.1% and 88.6%, 20.5% respectively. There was no significant difference between the two groups (P> 0.05). The effective rate of the treatment group was 91.1% and that of the control group was 72.7% (χ2 = 5.099, P <0.05). Conclusion The treatment of peptic ulcer with integrated traditional Chinese and western medicine is superior to western medicine alone and is worth further clinical promotion.