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通过不同时期儿童手指关节体征（下简称指征）与Ｘ线的检出情况、指征与Ｘ线的对比、指征的Ｘ线监测、踝关节功能障碍所致下蹲不全与踝关节Ｘ线间关系的研究看出：引起关节功能障碍的主要原因是关节相关软组织损害；骨软骨和关节相关软组织损害可各自单独发生，可同时发生，也可先出现一种组织损害后再相继出现另一种损害，出现次序无固定关系；单独关节相关软组织损害也可导致关节畸形和功能障碍。故骨软骨和关节相关软组织损害是大骨节病的两种基本组织病理损害类型。为了防治目的，在大骨节病诊断中按此分型较为确切和实用。
Through the detection of X-ray in children’s finger joints at different periods, the indications were compared with the X-ray, the X-ray monitoring of the indications, the crouching due to ankle dysfunction and the ankle joint X-ray The relationship between the study shows that: the main cause of joint dysfunction caused by joint-related soft tissue damage; osteochondral and joint-related soft tissue damage can occur separately, can occur simultaneously, but also a tissue damage occurred before another one after another The kind of damage, there is no fixed relationship between the order; joint-related soft tissue damage can also lead to joint deformities and dysfunction. Therefore, cartilage and joint-related soft tissue damage is the two basic histopathological lesions of Kashin-Beck disease. In order to prevent the purpose, in the diagnosis of Kashin-Beck disease in accordance with this type is more accurate and practical.