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目的探讨出生缺陷发生的种类、相关因素及应对措施。方法对6年间台州市路桥区出生缺陷500例进行回顾性临床分析。采用B超扫描、母体组织或血、尿检查胎儿是否先天缺陷。结果 6年间出生缺陷的发生率14.8‰,男女之比1.63∶1,两性畸形发生率0.4%;出生缺陷农村比城镇高出5倍;出生缺陷主要为先天性心脏病、先天性梅毒儿、唇腭裂。产前确诊240例,其中产前行治疗性引产170例,产前确诊比占48.0%。结论出生缺陷儿的发生与营养、季节、感染、环境及遗传因素有关。产前确诊减少了先天缺陷儿的出生,提高出生人口素质。
Objective To explore the types of birth defects, related factors and countermeasures. Methods Retrospective clinical analysis of 500 cases of birth defects in Luqiao District of Taizhou in 6 years. Using B-scan, maternal tissue or blood, urine to check whether the fetus birth defects. Results The incidence of birth defects in 6 years was 14.8 ‰, the ratio of male to female was 1.63:1, the incidence of genital malformations was 0.4%. Birth defects in rural areas were five times higher than those in urban areas. Birth defects were mainly congenital heart disease, congenital syphilis, Cleft palate. Prenatal diagnosis of 240 cases, of which 170 cases of prenatal treatment of induced labor, prenatal diagnosis accounted for 48.0%. Conclusions The incidence of birth defects is related to nutrition, season, infection, environment and genetic factors. Prenatal diagnosis reduces the birth of birth defects and improve the quality of the birth population.