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R-蛋白作为B_(12)的天然结合剂,除了与B_(12)有较强的结合力外,也与葡萄糖-6-磷酸脱氢酶-B_(12)复合物(G6PDH-B_(12))有一定的结合力.当没有B_(12)存在时,R-蛋白能与G6PDH-B_(12)结合并使其催化活性降低约40%.但当B_(12)存在时,则按样品中B_(12)的量使G6PDH-B_(12)重新获得一定量的活性.这种G6PDH-B_(12)酶复合物活性的重活化只发生在很窄的B_(12)浓度范
As a natural binding agent of B 12, R-protein also binds to glucose-6-phosphate dehydrogenase-B 12 complex (G6PDH-B 12 ) In the presence of B_ (12), R-protein can bind to G6PDH-B_ (12) and reduce its catalytic activity by about 40% in the absence of B_ (12) The amount of B_ (12) in the sample regained a certain amount of activity of G6PDH-B_ (12) .The activity of this G6PDH-B_ (12) enzyme activity was only activated at a very narrow B_ (12)