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本文作者以肝组织像为指标,研究了对27例确诊为非甲非乙型慢性肝炎患者单独给予α干扰素的有效用量,以及并用OK·432的效果。结果表明,单独给予α干扰素组:每天肌肉注射9～4.5×10~6u,4周后转氨酶可见明显改善,但发病后长期经过的病例肝硬化病例及肝细胞脂肪变化组无效的病例多。α干扰素和OK·432并用组:对1组无效的病例也有效,3例治疗9～24个月的患者,治疗后肝功能值恢复正常,而且持续一年以上。单独给予OK·432组:未见转氨酶的改善。以上结果提示,α干扰素治疗非甲非乙型慢性肝炎有效率在70％以上,而少量
In this study, the authors used an image of liver tissue as an index to study the effective dosage of IFN-α administered alone in 27 patients with CHD who were diagnosed as non-A, and the combined use of OK · 432. The results showed that interferon α alone was administrated intramuscularly for 9 ~ 4.5 × 10 ~ 6u intramuscularly every four weeks. However, aminotransferase could be obviously improved after 4 weeks. However, there were many cases of chronic liver cirrhosis and hepatocyte fat change after the onset of disease. α interferon and OK · 432 combined group: 1 group of invalid cases also effective, 3 cases of 9 to 24 months of treatment, liver function returned to normal after treatment, and lasted for more than a year. OK group 432 alone: no improvement of transaminases. The above results suggest that interferon alpha treatment of non-A non-B chronic hepatitis effective rate of 70% or more, and a small amount