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为临床安全应用马应龙麝香消炎去腐生肌软膏而观察其局部作用及毒性。动物实验按不同项目设40%,20%,15%,10%不同浓度实验组与基质对照组。本品对豚鼠皮肤的局部作用急性毒性、长期毒性、皮肤刺激试验、皮肤过敏试验等八项实验。观察一般行为活动、食量、二便、皮肤粘膜、心率、心律、血像、肝肾功能,并作皮肤、脑、心、肝、脾、肺、肾、睾丸(或卵巢)组织学检查。结果各剂量组与基质对照组间未见明显差异,证明本品基本无毒,无刺激性,无过敏性,并可加快破损皮肤愈合。
For the clinical safety application of Ma Ying-long musk anti-inflammatory to saproergogenic ointment and observe its local effects and toxicity. Animal experiments were set up according to different projects for 40%, 20%, 15%, and 10% for different concentrations of experimental group and matrix control group. The product of the guinea pig skin local acute toxicity, long-term toxicity, skin irritation test, skin allergy test and other eight experiments. Observe general behavioral activities, food intake, stool, skin and mucous membrane, heart rate, heart rate, blood, liver and kidney function, and perform histological examination of skin, brain, heart, liver, spleen, lung, kidney, and testis (or ovary). Results No significant difference was found between each dose group and the matrix control group, which proved that the product is basically non-toxic, non-irritating, non-allergic, and can accelerate the healing of damaged skin.