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目的:探明围产儿尸检中先天性心血管畸形(简称先心病)的比较发生率及其对临床的意义。方法:通过对心脏标本的复查,结合临床、病理特点进行归类和分析。结果:本组先心病发生率占围产儿尸检的22.3%,其中常见的致死性畸形依次为婴儿型主动脉缩窄、大动脉易位、左室发育不良、永存动脉干、心内膜垫缺损、单心室和肺静脉畸形引流等;在非致死性畸形中,以房间隔缺损和室间隔缺损最为多见。结论:先心病是导致围产儿死亡的重要原因之一,临床上有待不断提高产前诊断水平。
Objective: To investigate the incidence of congenital cardiovascular malformation in perinatal autopsy (referred to as CHD) and its clinical significance. Methods: Through the review of the heart specimens, combined with clinical and pathological features were classified and analyzed. Results: The incidence of congenital heart disease in this group accounted for 22.3% of autopsy perinatal children, of which the common fatal deformities were infantile aortic constriction, aortic translocation, left ventricular dysplasia, perpetual survival of the artery, endocardial cushion Defects, single ventricle and pulmonary venous anomalies drainage; in non-fatal deformity, with atrial septal defect and ventricular septal defect most common. Conclusions: Congenital heart disease is one of the important causes of perinatal death. Clinically, the level of prenatal diagnosis needs to be continuously improved.