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四环素与活体骨组织有特殊的亲和力,用它作为标记物以研究不同实验条件下骨的代谢情况(如赛跑、切除甲状旁腺、航天失重等),既安全又方便,还可作定量分析.从我们查阅的文献了解到,英国的Sissons于1962年报告过这项工作.1980年湖南医学院郭绢霞等报告,人的板层骨形成速率(四环素标记)为1微米/日.1985年沈士良报告,在模拟失重条件下大鼠骨形成速率为4～5微米/日;又称鼠下门齿成骨速度最
Tetracycline has special affinity with living bone tissue. It can be used as a marker to study bone metabolism under different experimental conditions (such as racing, parathyroid glands removal, weight loss on aerospace, etc.), and is also safe and convenient for quantitative analysis. According to the literature we have read, this work was reported by Sissons in the United Kingdom in 1962. Guo Shu-Xia et al. (Hunan Medical College, 1980) reported that human lamellar bone formation rate (tetracycline marker) was 1 micron per day. Shinshiliang reported that in the simulated weightlessness rat bone formation rate of 4 to 5 microns / day; also known as the lowest rate of incisor odontogenesis