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目的:观察舒血宁注射液联合低分子肝素钙注射液治疗急性缺血性脑卒中的效果。方法:选取112例急性缺血性脑卒中患者随机分为对照组和治疗组各56例,2组均给予常规的治疗,治疗组加用舒血宁注射液联合低分子肝素钙注射液治疗,对照组加用阿司匹林肠溶片、马来酸桂哌齐特注射液和依达拉奉注射液治疗,2组均连续治疗2周。比较2组治疗前后神经功能恢复情况、临床疗效及不良反应情况等。结果:对照组总有效率为76.8%,治疗组总有效率为91.1%,2组比较,差异有统计学意义(P<0.05)。治疗1周、2周后,2组神经功能损伤评分均较治疗前有所降低(P<0.05),治疗组神经功能损伤评分均低于对照组(P<0.05)。结论:在常规治疗的基础上,使用舒血宁注射液联合低分子肝素钙注射液治疗急性缺血性脑卒中,可显著恢复患者的神经功能,提高临床治疗效果。
Objective: To observe the effect of Shuxuening injection and low molecular weight heparin injection on acute ischemic stroke. Methods: One hundred and twelve patients with acute ischemic stroke were randomly divided into control group and treatment group (n = 56). The two groups were given routine treatment. The treatment group was treated with Shuxuening injection combined with low molecular weight heparin calcium injection, Control group plus aspirin enteric-coated tablets, cinepazide maleate injection and edaravone injection treatment, two groups were treated for 2 weeks. The neurological function recovery, clinical efficacy and adverse reactions of the two groups were compared before and after treatment. Results: The total effective rate of the control group was 76.8%, the total effective rate of the treatment group was 91.1%. There was significant difference between the two groups (P <0.05). After 1 and 2 weeks of treatment, the score of neurological impairment in both groups was lower than that before treatment (P <0.05), and the score of neurological impairment in the treatment group was lower than that of the control group (P <0.05). Conclusion: On the basis of routine treatment, Shuxuening injection combined with low molecular weight heparin injection in the treatment of acute ischemic stroke can significantly restore the neurological function of patients and improve the clinical curative effect.