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目的:探讨广西地区2006~2009年肾移植术后肺部感染的病原学特点,为经验性抗感染治疗提供用药参考。方法:对69例肾移植术后肺部感染病例进行回顾性分析。结果:49例检出病原体,按出现频度高低依次为普通细菌39例次,其次为真菌22例次,肺炎支原体血清学试验阳性8例次;结核杆菌3例次、衣原体血清学试验阳性3例次;巨细胞病毒抗体及基因阳性2例次;卡氏肺囊虫1例。检出病原体病例中,2种以上混合感染34例(69.4%)。结论:广西地区肾移植术后肺部感染病原体检出结果较其他类似文献有一定差异。可能与广西独特的地域气候条件以及少数民族聚居区城乡居住环境和生活习惯有关。了解肾移植术后肺部感染的病原学特征,有利于及时有效地控制肺部感染,提高治疗成功率。
Objective: To explore the etiological characteristics of lung infection after kidney transplantation in Guangxi from 2006 to 2009, and to provide reference for the treatment of empiric anti-infection. Methods: A retrospective analysis of 69 cases of lung infection after renal transplantation was performed. Results: The pathogen was detected in 49 cases, followed by 39 cases of common bacteria, followed by 22 cases of fungi, 8 cases of Mycoplasma pneumoniae seropositivity, 3 cases of Mycobacterium tuberculosis and 3 cases of serotypes of Chlamydia pneumonia Cases; cytomegalovirus antibodies and genes were positive in 2 cases; Pneumocystis carinii in 1 case. Among the detected pathogen cases, 34 cases (69.4%) were infected with two or more mixed infections. Conclusion: The detection of pathogen of pulmonary infection in kidney transplant recipients in Guangxi is different from other similar articles. It may be related to the unique geographical and climatic conditions in Guangxi and the living environment and living habits of urban and rural residents inhabited by ethnic minorities. To understand the etiological characteristics of lung infection after renal transplantation is conducive to timely and effective control of lung infection and improve the success rate of treatment.