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目的探讨宫环形电切技术(LEEP术)在宫颈上皮内瘤样变(CIN)诊治中的应用价值。方法回顾性分析2005年1月-2007年1月我院134例应用LEEP术诊治的CIN患者的临床资料,观察手术时间、术中出血量、术后疗效,并对比分析阴道镜下活检病理结果与LEEP术后病理结果。结果134例患者行LEEP术前、后病理诊断级别相符102例,符合率为76.1%,升高14例,占10.5%,降低18例,占13.4%;手术时间为(4.7±1.1)min,术中出血量为(7.5±2.8)ml;阴道镜下活检病理诊断与LEEP术后标本病理诊断差异无统计学意义(P<0.05)。结论LEEP术可提高宫颈癌的早期诊断率、降低宫颈早期浸润癌的漏诊率,是诊断及治疗CIN病变的一种非常有临床价值的方法。
Objective To investigate the value of LEEP in diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods The clinical data of 134 CIN patients diagnosed and treated by LEEP from January 2005 to January 2007 in our hospital were retrospectively analyzed. The operative time, intraoperative blood loss and postoperative curative effect were observed. The colposcopic biopsy results were compared Postoperative pathological findings with LEEP. Results The pathological diagnosis level of 134 patients was consistent with LEEP preoperatively and postoperatively. The coincidence rate was 76.1%, elevated in 14 cases (10.5%) and decreased in 18 cases (13.4%). The operative time was (4.7 ± 1.1) min, The blood loss in operation was (7.5 ± 2.8) ml; there was no significant difference between colposcopy biopsy and LEEP postoperative pathological diagnosis (P <0.05). Conclusion LEEP can improve the early diagnosis rate of cervical cancer and reduce the misdiagnosis rate of early invasive carcinoma of the cervix. It is a very valuable method to diagnose and treat CIN.