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曾报道蝮蛇的50％乙醇提取物对链脲菌素(STZ)诱发糖尿病大鼠有降血糖作用,此次以晶状体中抗氧化物质的消长为指标,探讨了蝮蛇提取物对糖尿病性白内障大鼠的效果。 将蝮蛇干燥,制成粗末后以乙醇提取,得提取物(10.5％±0.8％)。实验使用7周龄Wistar系雄性大鼠。在给予STZ 6d后,经口给于干燥蝮蛇的50％乙醇提取物500mg/ml(500mg/kg)生理盐水混悬液,每日1次,连续给予34d。白内障的判定,在第40d采
It has been reported that the 50% ethanol extract of python has a hypoglycemic effect on streptozotocin (STZ)-induced diabetic rats. This time, the anti-oxidative substances in the lens were used as indicators to investigate the effect of python extract on diabetic cataract. Rat effect. The python was dried, made into a coarse powder and extracted with ethanol to obtain an extract (10.5%±0.8%). Seven-week-old Wistar male rats were used for the experiment. After 6 days of administration of STZ, a 500 mg/ml (500 mg/kg) saline suspension of dried 50% ethanol extract was given orally once a day for 34 days. Cataracts were determined on the 40th day