Evaluation of some ratio effects in ~(99m)Tc-MIBI imaging of breast tumors

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The effectiveness of using some ratios in 99mTc-MIBI imaging for the diagnosis of breast tumors was evaluated. After 100 patients with the breast tumor underwent 9mmTc-MIBI imaging, the ratios of tumor to contralateral uptake (T/N), tumor to heart uptake (T/H), and tumor to sternum uptake (T/S) were obtained and then analysed about their reproducibility and values in differentiating benign breast lesion the from malignant tumor. To detect breast cancers, the sensitivity, specificity and accuracy of T/N were 92%, 90% and 91%, respectively. However, those of T/S were 70% (p <0.01), 74% (p <0.05), 72% (p <0.01), and those of T/H were 74% (p <0.05), 76% (p >0.05), 75% (p <0.01). The average coefficients of variation(CV) of TIN, T/S and T/H were 9.439±9.712, 4.856±4.420 (p >0.05), and 3.736±3.489 (p <0.05). It was found that T/N had the best sensitivity, specificity and accuracy to detect the breast cancer, but its reproducibility is poor. On the other hand, T/H has better reproducibility. The effectiveness of using some ratios in 99mTc-MIBI imaging for the diagnosis of breast tumors was evaluated. After 100 patients with the breast tumor underwent 9mmTc-MIBI imaging, the ratios of tumor to contralateral uptake (T / N), tumor to heart uptake (T / H), and tumor to sternum uptake (T / S) were obtained and then analyzed about their reproducibility and values ​​in differentiating benign breast lesion the from malignant tumor. To detect breast cancers, the sensitivity, specificity and accuracy of T / The percentages of T / S were 70% (p <0.01), 74% (p <0.05), 72% (p <0.01), and those of T / S were 92%, 90% and 91% The average coefficients of variation (CV) of TIN, T / S and T / H were 9.439 ± 9.712, 4.856 (p <0.05) It was found that T / N had the best sensitivity, specificity and accuracy to detect the breast cancer, but its reproducibility is poor. On the other hand, T / H has better reproducibilit y
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